Supporting research with the potential to help children and animals
We’re proud to be collaborating with children’s charity Action Medical Research to help support two ongoing child-focused medical research studies. Both studies have the potential to benefit animals as well as children and to demonstrate the value of One Medicine, sharing learning between the worlds of human and veterinary medicine.
Humanimal Trust has contributed an initial £5,000 to each study, with the potential for further funding in subsequent years.
Study 1: Preventing infections and reducing the risk of antibiotic-resistant infections in critically ill children
The first study focuses on Humanimal Trust’s core aim of finding new ways to improve infection control and antibiotic resistance.
Study 2: Juvenile idiopathic arthritis: personalising drug treatment
The second study fits neatly into another of our core aims, finding new ways to treat bone and joint disease.
Osteosarcoma Research Study - University of Cambridge
Professor Matthew Allen and his team at the University of Cambridge are undertaking an "Evaluation of Metastasis Signature for Determining Rate of Disease Progression in Osteosarcoma".
Bone cancer is a common and potentially devastating condition affecting humans and companion animals. Primary bone cancers are those that originate in bone (e.g. Osteosarcoma and Ewing's sarcoma). Secondary bone cancers occur when a cancer from elsewhere in the body spreads (metasizes) to the bone (e.g. breast, lung and prostate cancer).
In both primary and secondary bone cancers, the growth of a tumour within bone leads to bone pain, bone damage and an increased risk of spontaneous fracture. Additionally, tumours that develop within bone have a high chance of subsequently spreading to vital organs such as the liver, lung and brain, often with fatal consequences.
The team at the University of Cambridge believes that controlling, or ideally preventing, the growth and subsequent spread of bone cancers to other organs will significantly extend life expectancy in cancer patients. To do this there is a need to understand the factors that determine whether bone cancers will spread outside the bone. By identifying these factors Professor Allen and his team hope to develop safe and selective treatments to target the tumours within bone.